These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. Colgate Sensitive Instant Relief Whitening Toothpaste 75 ml Pack of 5, Blocks Pain Instantly, Prevents Sensitivity, Gently Removes Stains (5 x 75 ml) 1,230 5 offers from 12.50 Colgate Sensitive Pro Relief Enamel Repair Toothpaste 75ml - 4 packs 94 22 offers from 14.14 Colgate Sensitive Instant Relief Enamel Repair Toothpaste 75 ml 190 SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Am J Dent. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Balevi B. 2016;8:114. Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. 1,2 Colgate Sensitive Instant Repair & Prevent Toothpaste 75ml - Superdrug Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. 2019;81:16. All rights reserved. J Dent. 1):8A-15A. Not all desensitizing toothpastes perform equally well. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. This toothpaste really does not help at all with symptoms of sensitive teeth. J Clin Dent. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. By using this website, you agree to our In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. J Dent Probl Solut. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. *with direct application and daily brushing. KruskalWallis test was used to compare treatment groups. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. 7 Ipsos, UK Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2 weeks trial, 192 respondents, 2016. Colgate Senstive Relief vs Sensodyne Toothpaste - Lowyat.NET Holland G, Narhi M, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. 3Intervention for Group C denotes Sensodyne Rapid Action. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Identifier NCT 04249336. Colgate Sensitive Pro-relief Instant Relief. Brush twice daily. COLGATE, Sensitive Pro Relief Original Toothpaste 110g | Watsons Singapore However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. These findings were similar to a previous study conducted by Schiff et al. Colgate Sensitive Pro-relief Repair & Prevent However, Pro-argin formulation showed 8% more improvement in clinical symptoms of DH than strontium acetate formulation one minute after application. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. 1). This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. Sealed channels protect against pain caused by hot, cold and sweet stimuli. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. 2010;23(Spec No A):14A-9A. It has stannous fluoride as an active ingredient. CONSORT flow chart. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds ID: NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336), Date of Registration: January 30, 2020 (Retrospectively registered). Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. 75 ml. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. Plus it has the freshness you trust from Colgate! 1997;24(11):80813. Instant effectiveness comparing Colgate Sensitive Pro-Relief and Colgate Sensitive Pro-Relief - Colgate Palmolive The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. Dentin hypersensitivity treatments work in one of two ways. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. Colgate Sensitive Instant Relief Toothpaste 75ml (Pack of 4) 2. 2017;59(4):4618. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. Great Savings & Free Delivery / Collection on many items. Lasting relief with 2x daily continued brushing. J Clin Dent. There was no statistically significant treatment difference between the two (p=0.499). Am J Dent. Many patients tolerate the pain of sensitive teeth because theyre unaware of simple but highly effective answers like Pro-Argin technology. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. The statistician was also kept blinded. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Oral dentifrices were provided to the subject free of cost. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. Free postage. J Dent Res. Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day.

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