Keep all drugs out of the reach of children and pets. This gives a total cumulative dose of 1,500 mg of Injectafer. Copyright 1996-2023 Cerner Multum, Inc. But some people have a delayed allergic reaction to certain drugs. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Many people using this medication do not have serious side effects. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. 2. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). You may also report side effects at https://www.fda.gov/medwatch. Iron infusions are given directly into a vein. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. This is only a brief summary of general information about this medicine. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Heart failure: Could a low sodium diet sometimes do more harm than good? The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. <> }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Side effects are uncomfortable reactions to medications or drugs. (And Injectafer is used to treat IDA.) Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. experience severe side effects, please seek medical attention right away and notify the ordering physician. These changes could help improve your anemia on a long-term basis. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. What Is the Cost of Whole Genome Sequencing (WGS)? Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Use of the term female in this article refers to sex assigned at birth. other treatments you receive, you will need to go back for several treatments with Venofer. Check with your pharmacist if you have questions about the best way to throw out drugs. This is why family members often have the same issues with drugs as others in theirfamily. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Details. All of the people took iron by mouth for 2 weeks. An iron infusion is a way to increase the body's iron levels quickly. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Keep all regular medical and laboratory appointments. Always review your medical history with the treatingphysician. upper respiratory infection. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Use Venofer as ordered by your doctor. But for other people, their IDA returns after treatment with Injectafer. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. This website is intended for use by US patients. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. chest pain. Low iron saturation, or iron deficiency, has various possible causes. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Can poor sleep impact your weight loss goals? Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Some drugs may have another patient information leaflet. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Do not start, stop, or change the dosage of any medicines without your doctor's approval. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. Details. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. For people with certain medical implants, such as pacemakers, an MRI may pose an . Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. In Canada - Call your doctor for medical advice about side effects. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. One study of just under 5000 HRT users found that 43% were affected. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. It is important to get each dose of this medication as scheduled. cough. You may report side effects to Health Canada at 1-866-234-2345. Taking a higher dose than needed can often lead to adverse effects. In one study, people were given either Injectafer or an iron replacement drug called Venofer. You may report side effects to the FDA at 1-800-332-1088. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Procedure Details Then the study was split into the following two groups, which are discussed below. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. This survey is being conducted by the WebMD marketing sciences department. If you notice any changes to your normal blood pressure, call your doctor right away. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. (For more information on Venofer, see the Injectafer vs. Venofer section above). If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Side effectsare uncomfortable reactions to medications or drugs. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. People from different ethnic backgrounds process medications differently. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Tell your doctor about the allergy and what signs you had. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Very bad and sometimes deadly allergic side effects have rarely happened. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Injectafer and Venofer can cause very similar side effects, but some different ones as well. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. You may also need to monitor your blood pressure at home. Iron infusion benefits. WebMD does not provide medical advice, diagnosis or treatment. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. 5 0 obj Your healthcare provider will watch you closely for 30 minutes after each dose. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. And these two doses need to be separated by at least 7 days. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others.

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